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For decades, testosterone has been misunderstood as a “male-only” hormone. In reality, testosterone plays a vital role in women’s health as well—affecting everything from energy and libido to mood, muscle mass, and bone density. Recent clinical research, including Level 1 evidence from randomized controlled trials (RCTs) and systematic reviews, now supports the safe and effective use of testosterone therapy in women for targeted indications. At Liv HRT, we’re committed to providing evidence-backed treatments, and testosterone therapy is an important part of that conversation.
What Is Testosterone’s Role in Women?
Women naturally produce testosterone in the ovaries and adrenal glands, though in significantly lower amounts than men. Levels typically decline with age and more drastically after surgical or natural menopause. Symptoms of low testosterone in women can include:
- Reduced sexual desire and satisfaction
- Fatigue
- Mood instability or depression
- Loss of muscle strength
- Decreased bone density
Level 1 Evidence: What the Science Says
Several high-quality studies support the benefits of testosterone therapy for women, especially in the following areas:
1. Sexual Function and Desire
A landmark 2019 systematic review and meta-analysis published in The Lancet Diabetes & Endocrinology analyzed over 40 randomized controlled trials involving more than 8,000 women. The findings showed that testosterone therapy significantly improved:
- Sexual desire
- Arousal
- Orgasmic function
- Satisfaction
- Reduced sexual distress
Importantly, no serious adverse events were reported, reinforcing the therapy’s safety when properly monitored.
2. Mood and Well-Being
Emerging evidence also shows that testosterone can have a positive impact on mood and overall psychological well-being. Some RCTs suggest improvements in depressive symptoms and anxiety, particularly in postmenopausal women. While more studies are needed to confirm long-term effects, early findings are promising.
3. Muscle Mass and Physical Function
Testosterone therapy may help preserve lean body mass and improve strength in aging women. A 2021 meta-analysis published in The Journal of Clinical Endocrinology & Metabolism found small but statistically significant improvements in muscle mass and strength, particularly in women with clinically low testosterone levels.
4. Bone Health
Low testosterone may contribute to osteoporosis in women. While estrogen remains the primary hormone for bone protection, testosterone plays a supportive role. Some studies suggest that combination hormone therapy (including testosterone) may have greater benefits for bone mineral density than estrogen alone.
Is It Safe?
When testosterone is dosed appropriately—typically using low-dose transdermal creams or gels—it has been shown to be both safe and effective. Importantly, formulations should be tailored to female physiology, avoiding supraphysiologic doses that may increase the risk of side effects such as acne, hair growth, or voice changes.
Who Is a Candidate?
Testosterone therapy may benefit women who experience:
- Low libido or sexual dysfunction
- Fatigue or low energy
- Reduced muscle tone and endurance
- Depressive symptoms related to hormone imbalance
It is especially considered for postmenopausal women or those with surgically induced menopause (e.g., oophorectomy).
Personalized, Evidence-Based Care
At Liv HRT, our approach to testosterone therapy for women is science-driven and carefully personalized. We use state-of-the-art diagnostic tools to assess hormone levels and design treatment plans that restore balance—safely and effectively. Every therapy is overseen by experienced hormone specialists and titrated to meet each woman’s unique needs and goals.
Interested in Learning More?
Contact our team to find out if testosterone therapy is right for you. Empower your body. Reclaim your vitality—with evidence-based hormone care.
